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　　[Technology] Cars have become an indispensable part of our lives. The combination of steering wheel+shift lever+pedal seems to have become a natural way to control cars, but their respective mechanisms are rarely understood. Take the steering wheel in our hands as an example, the majority of riders are still vague about the common concepts of various steering systems, such as "the difference with hydraulic power" and "what is the variable power", and so on. Below, we will systematically introduce various common steering systems, answer these questions, and discuss the mysteries and mysteries of various steering systems with you.

　　Because of the long space, this paper introduces our most common system now, interprets "where does the power come from" and introduces the classification of power steering system.

　　Power steering, as its name implies, is to resist steering resistance by increasing external force, so that drivers can complete steering with less force. It is also called power steering. It was originally designed to make some large vehicles with heavy weight operate more easily, but now it has become very popular. It makes driving easier and easier, and makes vehicles more agile and improves safety to some extent. Power steering can be divided into two categories according to the different sources of power-hydraulic power and electric power.

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　　The origin of hydraulic power steering can be traced back to February, 1902. Frederick W. Lanchester of Britain invented "Cause the steering mechanism to be actuated by hydraulic power", that is, the hydraulic driving steering mechanism. After that, inventors in the United States and Canada successively registered patents for similar inventions. In automobile production, the commercial production of hydraulic power steering system was first realized, and it was named Hydraguide hydraulic steering system, and it was installed on Chrysler’s sixth generation Imperial in 1951. With the development of technology, the steering system with electronic pump instead of mechanical pump appears, so the current hydraulic power is mainly divided into mechanical hydraulic power and electronic hydraulic power. In addition, the electronic servo hydraulic power steering system is derived from the mechanical hydraulic power.

　　Let’s look at the main principle of mechanical hydraulic power steering, which is based on mechanical rack-and-pinion steering mechanism, and adds a whole set of hydraulic system, including liquid storage tank, hydraulic booster pump, mechanical valve connected with steering column, hydraulic cylinder on steering mechanism and the one that can push steering rod, etc.

　　The hydraulic pump provided by mechanical power steering is driven by a belt, which means that the steering pump can only run when the engine is running, which is why the steering wheel power disappears after the engine is turned off. On the steering machine, there is a mechanical valve that can rotate with the steering column. When the steering wheel does not rotate left and right, the pressure in the chambers on both sides of the piston is consistent and in a balanced state. When the steering wheel rotates, the mechanical valve connected to the steering column will be opened or closed accordingly, and the oil on one side will return directly to the oil storage tank without passing through the hydraulic cylinder, and the oil on the other side will continue to be injected into the hydraulic cylinder, so that the pressure difference between the two sides of the piston will be pushed under the action of hydraulic force, and then the auxiliary force will be generated to push the steering rod to steer the wheels, which greatly reduces the force required for us to turn the steering wheel.

　　Another advantage of hydraulic power steering system is to improve comfort and safety. When the wheels jump violently and the tires turn involuntarily when encountering potholes, the vibration can be well buffered and absorbed by the action of hydraulic pressure on the piston, which greatly reduces the vibration transmitted to the steering wheel. At the same time, this structure also improves the safety. For example, when a vehicle using the traditional rack-and-pinion mechanism turns, the tire suddenly changes direction when it encounters a pothole, and the rack will drive the gear to reverse the steering wheel, resulting in the situation of "beater", which is easy to hurt the driver’s hand, so there will be no such problem in a hydraulically assisted vehicle.

　　Mechanical hydraulic booster features:The whole system is a mechanical structure, from the mechanical hydraulic pump driven by the belt to the hydraulic mechanical valve body on the steering column, without any electronic system, with mature and stable technology, high reliability and wide application range. Even if the hydraulic system of the vehicle fails and loses power, it can still rely on the traditional rack and pinion mechanism for steering. Disadvantages are complex structure, large space occupation and high manufacturing cost, which also makes the maintenance difficult and costly. And because the hydraulic pump is driven by the engine belt, it will consume part of the power of the engine, which will affect the fuel economy and the power of the vehicle, especially for small-displacement vehicles with relatively weak power. In addition, the strength of the mechanical hydraulic power-assisted system is not adjustable, so it is difficult to take into account the different requirements for pointing accuracy when driving at low speed and high speed.

● Electro-hydraulic booster

　　The so-called Electro-hydraulic power steering (EHPS for short) has exactly the same principle as mechanical hydraulic power steering, but the biggest difference from mechanical hydraulic power steering is that instead of using a hydraulic pump driven by an engine through a belt, it is replaced by an electric pump.

　　The advantages of electro-hydraulic power assist are firstly reflected in energy consumption. First, the electronic pump driven by electric energy uses the electric energy output by the generator and the battery, and no longer consumes the power of the engine itself. The start and stop of the electronic pump are all controlled by the electronic system. When it is not steering, the electronic pump is turned off, unlike the mechanical hydraulic power assist pump, which is always linked with the engine, further reducing energy consumption.

　　Secondly, the electronic control unit of the electro-hydraulic power steering system can change the power of steering assistance by processing the information of sensors such as speed sensor, lateral acceleration sensor and steering angle sensor, and changing the flow rate of the electronic pump in real time, that is, the function of variable power assistance with speed. Of course, it is not only the electro-hydraulic power assist that can realize the variable power assist with speed. We will introduce various "variable" power assist steering systems in detail in later articles.

　　Electro-hydraulic power assist has been gradually popularized since the late 1990s, and brands such as,,,,, and have models using electro-hydraulic power assist system. We are familiar with, and other models use such a system.

"Triumph, old models and other models use electro-hydraulic power."

　　Why can’t electro-hydraulic assist replace mechanical hydraulic assist?

　　No matter from the aspects of technology, function or economy, electro-hydraulic power assistance has more advantages than mechanical hydraulic power assistance. However, at present, electro-hydraulic power assistance has not been able to replace mechanical hydraulic power assistance for the following reasons:

　　1. The cost of electro-hydraulic booster is higher. Compared with the mechanical hydraulic power-assisted system, after adding the electronic control system and replacing it with the electronic pump, the manufacturing cost of electronic hydraulic power-assisted system is higher, the technology is more complicated, and the difficulty and cost of maintenance are also increased.

　　2. The reliability is not as good as that of mechanical hydraulic booster. In addition to the failure of steering mechanism and hydraulic mechanism, electro-hydraulic power assist also increases the possibility of electrical system failure, so its reliability is not as good as that of traditional hydraulic power assist system.

　　3. The assistance is limited. Although the use of electronic pump has obvious advantages, it needs to be driven by the electric energy of the generator, and the vehicle-mounted generator itself and the maximum current it can provide are limited, so the power of the electronic pump is also limited, and the load it can carry is also limited. Therefore, at present, most of the models that use electro-hydraulic power are medium-sized vehicles. For vehicles that need greater assistance, the electro-hydraulic assistance system is beyond the reach.

　　4. Evolved mechanical hydraulic booster system. With the development of technology, the variable speed function of electro-hydraulic power-assisted system has been realized on the evolved mechanical hydraulic power-assisted system (using solenoid valve body technology), and even a variable speed ratio system has been derived from the mechanical hydraulic power-assisted steering system, so the mechanical hydraulic power-assisted system with higher reliability and load-bearing capacity is still welcomed by manufacturers.

　　BEIJING, March 1st (Xinhua)-On the 1st, at the press conference on the theme of "Authoritative Department Begins" held by the State Council Office, Jin Zhuanglong, Minister of Industry and Information Technology, said that the Ministry of Industry and Information Technology would anchor the strategic goals of manufacturing power, network power and digital China, take digital technology innovation breakthrough and application expansion as the main direction, and increase the integrated development of informationization and industrialization. Generally speaking, it is mainly in three aspects: one is the network platform, the other is the digital industry, and the other is the integrated development.

　　The first aspect is to solidly promote the construction of network infrastructure. China has built the world’s largest and technologically advanced network infrastructure, with Gigabit access capacity covering all prefecture-level cities. This year, the Ministry of Industry and Information Technology will further implement the construction of Gigabit cities. Not long ago, the Ministry of Industry and Information Technology held a Gigabit City Summit Forum to guide all localities and enterprises to speed up construction investment and accelerate the deep coverage of 5G and Gigabit optical networks. Study and formulate an action plan for the development of computing infrastructure and strengthen the construction of industrial Internet infrastructure.

　　The second aspect is to accelerate the development of the core industries of the digital economy. In 2022, China’s electronic information manufacturing industry achieved an operating income of 15.4 trillion yuan, and the software business income reached 10.8 trillion yuan, which laid a solid industrial and technical foundation for the integrated development of informationization and industrialization. The Ministry of Industry and Information Technology will accelerate the development of emerging digital industries such as artificial intelligence, big data, blockchain, cloud computing and network security, guide and support enterprises to increase investment in research and development, and improve the industrial level of communication equipment, core electronic components and ultra-high definition display. Promote the high-quality development of integrated circuits and industrial software industries. Build characteristic software colleges with high standards and create a number of famous software parks in China.

　　The third aspect is to vigorously promote the digital transformation of manufacturing industry. Study and formulate a roadmap for digital transformation of key industries and cultivate a number of digital transformation benchmarks. Promote the 5G Sailing Action Plan, deepen the integrated application of "5G+ Industrial Internet", promote the popularization and application of industrial Internet to industrial parks, and build a number of 5G fully connected factories. We will implement the smart manufacturing partner program and standard pilot actions, build a number of world-leading smart factories and smart supply chains, and develop new models and formats such as service-oriented manufacturing.

Order of Beijing Municipal People’s Government

　　No.181 　

　　"Measures for the prevention and control of environmental noise pollution in Beijing" has been adopted at the fifty-sixth executive meeting of the Municipal People’s Government on November 17, 2006, and is hereby promulgated and shall come into force as of January 1, 2007.

　　Mayor Wang Qishan

　　November 27th, 2006

　　Measures of Beijing Municipality for the Prevention and Control of Environmental Noise Pollution

Chapter I General Provisions

　　Article 1 In order to prevent and control environmental noise pollution, protect and improve the living environment, these Measures are formulated in accordance with the Law of People’s Republic of China (PRC) Municipality on the Prevention and Control of Environmental Noise Pollution and combined with the actual situation of this Municipality.

　　Article 2 These Measures shall apply to the prevention and control of environmental noise pollution within the administrative area of this Municipality.

　　Article 3 District and county people’s governments shall be responsible for the quality of acoustic environment within their respective administrative areas.

　　The municipal, district and county environmental protection administrative departments shall exercise unified supervision and management over the prevention and control of environmental noise pollution within their respective administrative areas.

　　The public security department is responsible for the supervision and management of social life noise and motor vehicle noise pollution prevention and control.

　　Road administrative departments are responsible for the supervision and management of noise pollution prevention and control of roads and urban rail transit.

　　The administrative department of quality and technical supervision shall supervise and manage the noise limits specified in the standards for industrial products and equipment.

　　Railway and civil aviation administrative departments shall, according to their respective responsibilities, supervise and manage the prevention and control of noise pollution of trains and civil aircraft respectively.

　　Planning, construction, industry and commerce, culture and other departments shall supervise and manage the prevention and control of environmental noise pollution according to their respective responsibilities.

　　Article 4 Residents’ committees and villagers’ committees shall assist the government and relevant departments in the supervision and management of noise pollution in residential areas and mediate disputes arising from noise among neighbors.

　　Article 5 All units and individuals have the obligation to protect the environment from noise pollution, and have the right to complain and report to the units and individuals that produce environmental noise pollution.

Chapter II Supervision and Administration of the Prevention and Control of Environmental Noise Pollution

　　Article 6 The district and county people’s governments shall, according to the standards of urban planning and acoustic environmental quality, delimit the applicable areas of various acoustic environmental quality standards within their respective administrative areas, and announce them to the public, and report them to the municipal environmental protection administrative department for the record.

　　The applicable area of environmental standards for aircraft noise around the airport shall be delineated by the municipal environmental protection administrative department in conjunction with the relevant municipal administrative departments and the relevant district and county people’s governments, and shall be implemented after being approved by the Municipal People’s government.

　　Article 7 When determining the construction layout, the planning administrative department shall reasonably delimit the noise-proof distance between the building and the traffic trunk line and put forward the corresponding planning and design requirements according to the national and municipal acoustic environment quality standards and the sound insulation design specifications for civil buildings.

　　Eighth new construction, renovation and expansion of construction projects that may produce noise pollution shall abide by the provisions of the state on environmental protection management of construction projects, and solicit the opinions of residents and units in the region before applying for environmental impact assessment and approval.

　　Article 9 The sound insulation quality of newly-built civil buildings to external environmental noise and supporting public facilities such as water supply, heating, elevators and ventilation shall conform to the relevant national and municipal standards.

　　The planning administrative department shall strengthen the supervision of the implementation of the mandatory standards for the design quality of building sound insulation; The construction administrative department shall strengthen the supervision of the implementation of the mandatory standards for the construction quality of building sound insulation.

　　Article 10 Enterprises and institutions that cause serious environmental noise pollution in areas where noise-sensitive buildings are concentrated shall be ordered to treat within a time limit. Units that have been treated within a time limit shall complete the treatment tasks on schedule.

　　The deadline for the management of small enterprises and institutions shall be decided by the district and county environmental protection administrative departments. During the period of treatment within a time limit, the unit that has been treated within a time limit may be ordered to stop using the equipment and facilities that produce noise pollution or limit the running time of the equipment and facilities.

　　Eleventh residential buildings are not allowed to set up restaurants and entertainment places that may produce noise pollution.

　　When selling new residential buildings, the real estate development enterprise shall clearly indicate the building sound insulation situation of the residential buildings sold and the acoustic environment of the place where it is located.

　　Twelfth environmental protection administrative departments have the right to conduct on-site inspections of environmental noise pollution prevention and control units that emit environmental noise. If serious noise pollution is found in equipment and facilities during on-site inspection, it may be ordered to stop using the equipment and facilities or limit the running time of the equipment and facilities. The inspected unit shall stop or use the equipment and facilities within the specified time.

　　The units under inspection shall truthfully reflect the prevention and control of environmental noise pollution and provide necessary information on the prevention and control of environmental noise pollution.

　　Thirteenth environmental protection administrative departments to conduct on-site inspection of environmental noise pollution prevention and control, should produce valid law enforcement certificates, and keep the technical and commercial secrets for the inspected.

　　Fourteenth environmental protection administrative departments and other departments responsible for the supervision and management of noise pollution prevention and control shall announce to the public the names and contact information of the institutions responsible for accepting noise pollution complaints and reports.

Chapter III Prevention and Control of Construction Noise Pollution

　　Fifteenth construction work to the surrounding living environment, the construction unit shall take effective measures to prevent and control noise pollution, so that the noise emissions meet the national standards for environmental noise emission at the construction site. The cost of taking noise pollution prevention measures is included in the project cost.

　　Article 16 The construction unit shall formulate a management system for the prevention and control of noise pollution on the construction site and make a public announcement, and arrange the noise-producing equipment and facilities on the side far away from the residential area.

　　Seventeenth senior high school entrance examination, college entrance examination and other special periods stipulated by the Municipal People’s government, in addition to emergency repair, it is forbidden to engage in noise-producing construction work in the concentrated area of noise-sensitive buildings.

　　Eighteenth noise-sensitive buildings are concentrated in the area, and it is forbidden to carry out construction operations that produce noise pollution at night. However, the key projects of the state and this Municipality, emergency repair and rescue operations, and continuous operations due to production process requirements and other special needs are excluded.

　　If it is really necessary to carry out construction work at night for key projects of the state and this Municipality due to production process requirements or other special needs, it shall obtain the approval document issued by the construction administrative department where the project is located.

　　Nineteenth night construction work, it should be announced to the surrounding residents. The contents of the announcement include: the name of the construction project, the name of the construction unit, the approval number of night construction, the start and end time of night construction, the content of night construction, the person in charge of the site and its contact information, and the supervision telephone number.

Chapter IV Prevention and Control of Traffic Noise Pollution

　　Article 20 When newly built, rebuilt or expanded expressways, expressways, trunk roads, urban elevated roads, railways and urban tracks pass through areas where existing noise-sensitive buildings are concentrated, noise pollution prevention measures shall be taken. The cost of taking noise pollution prevention measures is included in the project cost.

　　Twenty-first in the construction of noise-sensitive structures on both sides of existing roads, railways and urban tracks, the construction unit shall take necessary measures to prevent and control noise pollution. Make the indoor acoustic environment quality in noise-sensitive structures meet the national standards.

　　Article 22 The noise emission of motor vehicles in use in this Municipality shall conform to the noise emission standards for motor vehicles in use stipulated by the state.

　　In-use motor vehicle silencers and other noise pollution prevention and control equipment should be used normally, and modification, removal or idleness are prohibited.

　　It is forbidden to install and use external audio equipment except special vehicles. Special vehicles equipped with external audio equipment shall be used in accordance with regulations.

　　Article 23 The public security department may, according to the needs, designate road sections where traffic is restricted at night and areas where honking is prohibited around residential areas, and clearly define the time periods when traffic is restricted and honking is prohibited.

　　Twenty-fourth motor vehicle parking lot, waiting station, should choose a reasonable location or take other effective measures to reduce the impact of noise generated by vehicles on the surrounding living environment.

　　Twenty-fifth railway locomotives in the city built-up area, should be in accordance with the relevant provisions of the state and the city to limit the whistle.

　　Article 26 When formulating flight procedures at airports, relevant departments should consider the impact of noise and try to avoid areas where noise-sensitive buildings are concentrated.

　　When a civil aircraft takes off, lands or flies at low altitude, it shall abide by the prescribed flight procedures.

　　Twenty-seventh in the construction of buildings in the area where the aircraft noise environmental standards are applicable, the provisions of the applicable areas of the corresponding standards shall be implemented.

Chapter V Prevention and Control of Noise Pollution in Social Life

　　Twenty-eighth it is forbidden for any unit or individual to use audio equipment that interferes with others in areas where noise-sensitive buildings are concentrated. However, in the following circumstances, it is allowed to be used for a certain period of time, and the volume is controlled:　

　　(a) large-scale social activities approved according to law;

　　(2) Class and break exercise;

　　(3) Emergency situations such as emergency rescue and disaster relief.

　　It is forbidden for commercial activities to use audio equipment outdoors or to attract customers by other methods of making noise and interfere with the surrounding living environment.

　　Twenty-ninth in the streets, squares, parks and other public places to organize entertainment, assembly and other activities, the use of household appliances, musical instruments and other audio equipment, should be controlled to avoid interference with the surrounding living environment.

　　Thirtieth processing, maintenance, catering, entertainment, fitness, supermarkets and other commercial service operators should take effective measures to prevent noise from production and business activities from interfering with the surrounding living environment.

　　Article 31 Where air conditioners, cooling towers and other equipment and facilities that may produce environmental noise pollution are used in commercial activities, their managers shall take effective measures to make their boundary noise meet the environmental noise emission standards stipulated by the state.

　　Thirty-second motor vehicle burglar alarms produced and sold in this Municipality shall meet the standards prescribed by the state.

　　Motor vehicles in this Municipality are not allowed to install and use motor vehicle burglar alarms that do not meet the standards.

　　The municipal administrative department of quality and technical supervision shall announce to the public the motor vehicle burglar alarm that does not meet the standard.

　　Thirty-third in the area where noise-sensitive buildings are concentrated, no noise shall be generated when setting or lifting the motor vehicle alert or looking for a car.

　　After the vehicle burglar alarm sounds, the user should deal with it in time to avoid disturbing the surrounding living environment by ringing for a long time.

　　Thirty-fourth use of household appliances, musical instruments or other indoor entertainment activities, should control the volume or take other effective measures to avoid interference with the surrounding living environment.

　　Thirty-fifth statutory rest days, holidays and working days from 12: 00 to 14: 00, from 18: 00 to 8: 00 the next day, it is forbidden to carry out decoration work that produces noise in residential buildings that have been completed and delivered. If renovation work is carried out in other time periods, measures shall be taken to reduce the interference to the surrounding living environment.

　　If renovation work is carried out in other buildings that have been completed and delivered for use, measures shall be taken to reduce the interference to the surrounding living environment.

Chapter VI Legal Liability

　　Thirty-sixth in violation of the provisions of the first paragraph of article tenth of these measures, did not complete the task of governance, by the competent administrative department of environmental protection at a fine of 30 thousand yuan; If the circumstances are serious, the municipal or district/county people’s government shall order it to suspend business, relocate or close down.

　　Thirty-seventh in violation of the provisions of the first paragraph of Article 12 of these measures, the inspected unit fails to stop or use the equipment and facilities that cause serious noise pollution within the specified time, and the competent administrative department of environmental protection shall impose a fine of not more than 30,000 yuan.

　　Article 38 In violation of the provisions of Article 16 of these measures, if the construction unit fails to formulate the management system for the prevention and control of noise pollution on the construction site and fails to arrange the noise-producing equipment and facilities far away from the residential area, the comprehensive law enforcement department of urban management shall order it to make corrections and may impose a fine of not less than 10,000 yuan but not more than 30,000 yuan.

　　Article 39 Whoever, in violation of the provisions of Article 17 of these measures, engages in noise-producing construction operations in noise-sensitive buildings concentrated areas during the senior high school entrance examination and college entrance examination and other special periods stipulated by the Municipal People’s Government, shall be ordered by the comprehensive law enforcement department of urban management to stop the illegal act and be fined not less than 10,000 yuan but not more than 30,000 yuan.

　　Fortieth in violation of the provisions of the second paragraph of Article 18 of these measures, without obtaining the approval documents for night construction, the comprehensive law enforcement department of urban management shall order it to stop the illegal act and impose a fine of 10,000 yuan to 30,000 yuan.

　　Forty-first in violation of the provisions of article nineteenth of these measures, the night construction work did not announce the relevant contents to the surrounding residents, and the comprehensive law enforcement department of urban management shall order it to make corrections and impose a fine of more than 5,000 yuan in 1000 yuan.

　　Article 42 If, in violation of the provisions of Article 30 of these Measures, operators of processing, maintenance, catering, entertainment, fitness, supermarkets and other commercial services fail to take effective measures, and noise generated by production and business activities interferes with the surrounding living environment, the competent administrative department of environmental protection shall order them to make corrections; Refuses to correct, a fine of 30 thousand yuan.

　　Forty-third in violation of the provisions of these measures, one of the following acts shall be given a warning by the public security department, and if it is not corrected after the warning, it shall be fined from 200 yuan to 500 yuan:

　　(a) the use of audio equipment that interferes with the surrounding living environment in areas where noise-sensitive buildings are concentrated;

　　(2) Commercial activities use audio equipment outdoors or use other noise-making methods to attract customers and interfere with the surrounding living environment;

　　(three) in the streets, squares, parks and other public places to organize entertainment, assembly and other activities, the use of audio equipment, noise interference around the living environment;

　　(four) not in accordance with the provisions of the second paragraph of article thirty-third of these measures in a timely manner, the motor vehicle burglar alarm sounded for a long time, which interfered with the surrounding living environment;

　　(five) did not control the volume or take measures in accordance with the provisions of article thirty-fourth of these measures, and the noise emitted from the family room interfered with the surrounding living environment;

　　(six) failing to carry out decoration work in accordance with the provisions of article thirty-fifth, which interferes with the surrounding living environment.

　　Forty-fourth in violation of these measures, in accordance with the planning, construction, industry and commerce, culture, transportation, quality and technical supervision and other relevant laws, regulations and rules should be dealt with, by the relevant departments in accordance with the law.

　　Forty-fifth units and individuals that are harmed by environmental noise pollution have the right to ask the perpetrators to eliminate the harm; Causing losses, have the right to claim compensation according to law.

　　Disputes over the liability for compensation and the amount of compensation may be settled through mediation by the competent administrative department of environmental protection or other supervisory and administrative departments, institutions and people’s mediation committees for the prevention and control of environmental noise pollution at the request of the parties concerned; If mediation fails, the parties may bring a suit in a people’s court. The parties may also directly bring a suit in a people’s court.

　　Article 46 If an administrative organ and its staff who are responsible for the supervision and management of the prevention and control of environmental noise pollution fail to perform their duties in accordance with the law, resulting in serious consequences, the competent administrative organ at a higher level or the supervisory organ shall order it to make corrections, and the directly responsible person in charge and other directly responsible persons shall be given administrative sanctions according to law; If a crime is constituted, criminal responsibility shall be investigated according to law.

Chapter VII Supplementary Provisions

　　Article 47 These Measures shall come into force as of January 1, 2007. The Interim Measures for the Administration of Environmental Noise in Beijing promulgated by the Municipal People’s Government on March 8, 1984 and revised by the Municipal People’s Government on December 31, 1997 shall be abolished at the same time. 　

[Editor’s Note] "We should develop traditional Chinese medicine, pay attention to interpreting the principles of traditional Chinese medicine with modern science, and take the road of combining traditional Chinese and western medicine." On May 12th, General Secretary of the Supreme Leader once again asked about Chinese medicine during his inspection tour in Nanyang City, Henan Province, and put forward new and clear requirements for the further development of Chinese medicine.

Inheriting the essence, the development of traditional Chinese medicine can go back to ancient times; The development of traditional Chinese medicine will be clear and turbulent only when it is upright and innovative. Combined with the outstanding performance and experience of Chinese medicine in the treatment of COVID-19 epidemic, many Chinese medicine experts who have participated in the first-line anti-epidemic talk about their experiences, offering suggestions and suggestions for the high-quality development of Chinese medicine and protecting the health of all mankind.

Liu Qingquan, Dean of Beijing Hospital of Traditional Chinese Medicine affiliated to Capital Medical University. Photo courtesy of respondents

"The future development of Chinese medicine is to be brave and dare to combine with modern science and technology, and to be good at using modern science and technology language to make the oldest theory of Chinese medicine clear and clear, so that Chinese medicine can truly become a world medicine and a medical system that can be used by all countries and ethnic groups." Combined with the treatment of COVID-19 epidemic, Liu Qingquan, president of Beijing Hospital of Traditional Chinese Medicine affiliated to Capital Medical University, said that the integration of traditional Chinese medicine and western medicine is very important for the development of traditional Chinese medicine, and it may form a new medicine in the future. It not only has the traditional theoretical advantages of Chinese medicine classics, but also embodies the connotation of modern science and technology; It is neither classical Chinese medicine nor modern western medicine, but a complete medical system with complementary advantages.

On February 15th, 2020, in beijing ditan hospital, a pharmacist dispensed medicine for COVID-19 patients in a traditional Chinese medicine pharmacy. Xinhua News Agency reporter Yan Huanzong photo

The experience of Chinese and western collaborative treatment lays the foundation for the formation of new medicine.

In the process of fighting against the epidemic in COVID-19, the effective prescription of traditional Chinese medicine-"three drugs and three parties" screened out by clinic has played an important role.

Liu Qingquan, who once served as an expert in Hubei Central Steering Group and deputy head of the national expert group on medical treatment of traditional Chinese medicine, said that "three drugs and three parties" is actually a classic theory of China traditional Chinese medicine, a treatment method based on the experience of traditional Chinese medicine in treating plague for thousands of years, and a model for coping with new diseases.

"Through the analysis of COVID-19’s clinical characteristics, we have formed the idea that we can combine various effective prescriptions to treat, thus forming the basic idea of’ three parties and three drugs’, that is, according to the changes of etiology and different stages of illness, we can adjust and combine to form effective treatment methods. This proves the greatness and correctness of the theory of traditional Chinese medicine and verifies that it conforms to scientific laws. " Liu Qingquan said.

"In the process of using’ three parties and three drugs’ treatment, we have also preliminarily explored and mastered some theoretical data of treating COVID-19 with traditional Chinese medicine. These studies prove that the basis of treating COVID-19 with traditional Chinese medicine is scientifically explained from different aspects, such as the adjustment of immune system and inflammatory system, which are the important pathological links that cause the disease to change, get worse and worse during the onset of COVID-19." Liu Qingquan analysis.

"In terms of coordinated treatment of Chinese and Western medicine, Chinese and Western medicine have their own strengths, and ultimately played a very important role in improving the success rate of severe and critical care and reducing the mortality rate, which proved the internal theoretical basis of coordinated treatment of Chinese and Western medicine and made some necessary preparations for exploring the organic integration of Chinese and Western medicine to form a new medicine." Liu Qingquan pointed out.

On February 25th, 2020, in Jiangxia Fangcang Hospital, Zhan Min (right), a medical staff member of the First Affiliated Hospital of Hunan University of Traditional Chinese Medicine, performed acupoint application therapy for COVID-19 patients. Xinhua News Agency reporter Shen Bohan photo

Exploration of Traditional Chinese Medicine Shelter Hospital Model of Infectious Diseases Hospital with Integrated Traditional Chinese and Western Medicine

In the process of Chinese medicine participating in Wuhan epidemic prevention and control and clinical treatment, Fangcang Hospital has become a medical pioneering work in a special period.

Liu Qingquan, a former president of Jiangxia Fangcang Hospital, was deeply touched by the experience of Chinese medicine taking over Fangcang Hospital. He said that the establishment of the shelter hospital is a very effective way to deal with sudden large-scale infectious diseases. In the shelter hospital, the treatment of light and ordinary patients with traditional Chinese medicine can effectively speed up the improvement of patients’ condition, reduce the occurrence of severe and critical diseases and reduce the mortality rate. In addition, because the source of infection is cut off in time, the control of virus transmission also plays a very important role.

Liu Qingquan believes that the experience and achievements gained by taking over Fangcang Hospital with traditional Chinese medicine technology to treat light and ordinary patients in COVID-19 have paved the way for the state to support the establishment of infectious disease hospitals and specialized hospitals with integrated traditional Chinese and western medicine. This will enable the future to quickly form a powerful force of combining traditional Chinese and western medicine, whether dealing with common infectious diseases or sudden new infectious diseases.

On May 23, 2021, the doctor set up the automatic decocting machine in Yingkou Hospital of Integrated Traditional Chinese and Western Medicine, Liaoning Province. Xinhua News Agency reporter Pan Xiaolong photo

Increase investment to support the construction of Chinese medicine institutions and Chinese medicine research.

Nowadays, in the treatment of many local epidemics distributed in China, the treatment scheme of traditional Chinese medicine is becoming more and more perfect and mature, and has achieved very good results. The methods of classified treatment and management of traditional Chinese medicine have become more and more popular and have become the consensus of the medical community.

"Compared with this treatment effect, there are too few medical institutions of Chinese medicine, which is a limitation to the role of Chinese medicine and its future development." Liu Qingquan called on the state to increase investment in TCM research and institution building. In dealing with infectious diseases, it is hoped that the state can support the establishment of infectious disease hospitals in mature areas with traditional Chinese medicine or integrated traditional Chinese and western medicine.

Liu Qingquan said that infectious diseases are the public enemy of mankind, regardless of Chinese medicine and western medicine, regardless of population and race. Therefore, I hope that China can make achievements in the construction of infectious disease hospitals with traditional Chinese medicine and integrated traditional Chinese and western medicine, and set an example for promoting the development of China medicine and even the world medicine. I hope that colleagues of Chinese and Western medicine can work together in Qi Xin to seize the opportunity and let the development of traditional Chinese medicine enter a new era.

　　On May 13th, on the first day of Tmall’s pre-emptive purchase of 618 countries, Taobao took the lead in playing the marketing strategy of "Wang Fried"-Kenny Lin, a national artist of "900 million girls’ dream", was officially declared as the brand ambassador of Taobao countries, and magical advertisements were placed in CCTV, online mainstream APP and offline over 50 cities, brainwashing consumers across the country: "Pay close attention to Taobao and receive state subsidies!" The big promotion policy of "national subsidy+Tmall 618 subsidy as low as 50% off" has strongly reached hundreds of millions of consumers.

　　In this year’s 618 event, Taobao also launched the "National Supplement Surprise Coupon" for the first time: users can grab the "National Supplement Surprise Coupon" which was launched for the first time and has the largest overlapping subsidy, and also participate in the interesting interaction of Kenny Lin, the brand ambassador of Taobao National Supplement; At the same time, watch the live broadcast of Kenny Lin on May 19th, and you will have a better chance to win the opportunity of "up to 10,000 yuan for national exemption". This "618" marketing campaign, which is based on policies, with stars as the guide, welfare as the spear and brand as the shield, once again breaks the routine and "updates" new marketing ideas, and also makes Taobao the first entrance for consumers to receive state subsidies.

　　"Hurry up and update" TVC’s magical brushing screen, releasing the whole world and detonating the country’s mind.

　　Consumers are blown in mid-air by strong winds, grabbing mobile phones passing by; The person at the forefront of the team reached out and grabbed Kenny Lin’s skirts, and shouted with joy, "Hurry up and update!"

　　The magic advertisement in just 15 seconds directly visualizes the core idea of Taobao’s national compensation marketing: "People are blown by strong winds" vividly interprets "the wind of Taobao’s national compensation is too strong"; All kinds of home appliances that have been blown away intuitively show the rich categories of Taobao’s national supplement; The action of "Hurry up to update" is a pun, which skillfully connects the homonym of the name of Kenny Lin, the ambassador of Taobao’s national subsidy brand, with "Hurry up to receive the national subsidy from Taobao", and makes a heavy discount of "make up for it, as low as 50% off", which quickly attracts users’ attention and grabs users’ minds.

　　In addition, Taobao also released several other magical TVCs, such as "Catch Kenny Lin in mid-air", "Kenny Lin City Gate Catch New Household Appliances" and "Delivery Master Catch Kenny Lin". Together with Dafeng Creative TVC, it interestingly explained the four core points of this national supplement: supplement and supplement, rich categories, new products and service mentality, which directly highlighted the interesting marketing style of this 618 Taobao.

　　As the ambassador of Taobao’s national subsidy brand, Kenny Lin’s label setting has always been highly consistent with Taobao’s "affordable and interesting" platform image, and its name of "update" has formed a natural memory point with "grasping Taobao’s national subsidy". In addition, the audience flow brought by last year’s hot works such as "The Story of a Rose" and "With the Phoenix" has contributed to the spread of "grasping the update".

　　In order to detonate the communication potential, Taobao released a global bombing combination boxing: CCTV launched to strengthen the credibility of the policy, covering all ages and nationwide markets; Online mainstream apps open screens and information flow advertisements accurately attack young users; The offline 50+ city business circle will be launched to create an immersive "updated" advertising experience.

　　Long-term marketing drives brand value to upgrade, grasps policy dividend and highlights brand responsibility.

　　When the demonic brainwashing "hurry to update" TVC swept the business circle of 50 cities across the country, Taobao’s national compensation marketing offensive became stronger and stronger-on May 19th, Taobao’s national compensation brand ambassador Kenny Lin will conduct a live broadcast. At that time, Kenny Lin will carry out a series of interesting interactions around the national subsidy, and will also give users a bonus of 10,000 yuan, star signatures, 50 rounds of red packets of rain and other super benefits, so as to create a saturated communication of "offline detonation+online fission" and continue to create a 618 marketing fever.

　　Behind the lively entertainment marketing is Taobao’s deep response to the national subsidy policy: whether it is a big promotion discount, extra subsidies for trade-in, more brands and categories, more urban coverage, or the service of subsidizing 10,000 new products, large and small household appliances and home improvement, users can feel the peace of mind of Taobao’s in-depth implementation of the national subsidy policy as long as they log on to Taobao. This kind of play that turns policy potential energy into brand long-term value also adds weight to Taobao’s "good heart" as a user.

　　It is worth noting that this time, Taobao, the national supplement, assembled 100 head brands for the first time to jointly make profits. Under the call of the platform, many brands actively responded to the national subsidy activities, and strongly conveyed the mind of "leading the country to make up for Taobao" by directly benefiting consumers. The collective call of many merchants not only enriched the lineup of activities, but also helped improve Taobao’s national compensation strategy. Especially under the premise that the national subsidy policy has restrictions on each citizen’s eligibility and quota, Taobao, which has gathered the most comprehensive categories, the best subsidies and exclusive service rights, has naturally become the "first entrance" for consumers to choose to receive national subsidies.

　　Just like this magical TVC advertisement, Taobao’s combination of "national dividend+traffic leverage+global communication" has once again "updated" the new example of e-commerce platform 618 marketing.

　　Recently, according to the China Youth Daily, "Ginger Soaks Foot" and "Drinking Tea for Beauty" … … With the increasing pressure of life, not only the post-90s generation who entered the workplace, but also many college students have begun to try various methods of health preservation. Health preservation is no longer the exclusive word of the elderly or middle-aged people, and the young campus groups represented by college students are constantly adjusting their lifestyles and advocating a healthier life and rest. Why are this wave of college students "trapped in health care" and "selling the old"? Many college students said that this is a way of "self-mockery" to fight anxiety and pressure.

　　In many people’s cognition, college students are relaxed and chic, and can have fun relatively freely. But in fact, many college students are very bitter and tired now. It is not unusual to do homework, research and activities in class until early morning or even later.

　　Under such a realistic background, it is not difficult to understand that many college students are "trapped in health preservation". Recently, a "2018 Life Consumption Trend Report" shows that based on the search volume of "Lycium barbarum" on the e-commerce platform of all ages, the proportion of search volume after 1995 increased significantly in September 2017. Honey, Lycium barbarum, whey protein, health tea and enzymes are the health foods that are keen on after 1995.

　　When I was in college, I was also a "busy maniac". I was really working hard. My meals and sleep were irregular, and I also had a tendency to overeat. At that time, I thought I was still young, so I indulged myself too much and was indifferent to some early warning signals of my body. But now, nearly a year after graduation, all kinds of physical and mental discomforts have emerged, and I realize that "karma" has come and I want to "pay my debts". Therefore, now I will also force myself to keep fit, such as drinking more hot water, going to massage, eating more healthy food and running to and from work.

　　The meaning of life is not temporary, but long-term. To quote a very fashionable online buzzword recently, "People who work too hard can’t run far". Who doesn’t want to "run away" on the road of life? So, please do it and cherish it.

　　Of course, it is not enough to rely solely on the self-awakening of young people, but also to exert efforts at the social level. To put it bluntly, in addition to focusing on the "burden reduction" of primary and secondary school students, the social level should also focus on the "burden reduction" of young people represented by college students. There is no denying that the latter should be under pressure and responsible, and strive hard to realize their own value and social value, but all this should not be at the expense of health. It should be a social consensus that only a good body and a healthy lifestyle can create more shocking values.

　　Mocheng

Investigation report on "4 12" major road traffic accident in Lianyungang section of Lianhuo Expressway　

2018 April 12, 2008 A major road traffic accident occurred in Lianyungang section of Lianhuo Expressway, Jiangsu Province, causing 8 deaths, 1 serious injury and 36 minor injuries, and the direct economic loss was about 7.42 million yuan.

After the accident, the CPC Central Committee and the State Council attached great importance to it, and Comrade members of the Political Bureau of the Communist Party of China Central Committee and Liu He, Vice Premier of the People’s Republic of China made important instructions. Li Wei, Vice Minister of Public Security, instructed to find out the reasons and cooperate with the aftermath. Fei Gaoyun, member of the Standing Committee of the Provincial Party Committee, secretary of the Political and Legal Committee, vice governor, Liu Yang, vice governor and director of the Public Security Department, and leaders of Lianyungang Municipal Party Committee and Municipal Government respectively gave instructions, demanding that all efforts be made to rescue the wounded, thoroughly investigate the cause of the accident and do a good job in the aftermath.

According to the Law on Safety in Production, the Law on Road Traffic Safety and the Regulations on Reporting, Investigation and Handling of Production Safety Accidents (Order No.493 of the State Council) and other laws and regulations, Lianyungang Municipal People’s Government has established the Lianyungang Section of Lianhuo Expressway "4", which is led by the Municipal Public Security Bureau and attended by the Municipal Transportation Bureau, the Safety Supervision Bureau and the Federation of Trade Unions.·12 "A large road traffic accident investigation team (hereinafter referred to as the accident investigation team) carried out accident investigation, and the accident investigation team also invited the Municipal Supervision Committee to participate.

According to the principles of "four no-misses" and "scientific rigor, compliance with laws and regulations, seeking truth from facts and paying attention to practical results", the accident investigation team found out the process, causes, casualties and direct economic losses of the accident through on-site inspection, investigation and evidence collection, identified the nature and responsibility of the accident, put forward suggestions on handling the responsible personnel and units, and put forward accident prevention and prevention according to the causes and outstanding problems exposed. The relevant situation is now reported as follows:

One,Basic situation

(a) the accident vehicle situation

1.Yu AE4555 large ordinary bus: the model of this car is Jinlong brand XMQ6129FYD 3A, Xiamen Jinlong United Automobile Industry Co., Ltd., the vehicle factory date is October 11, 2012, the vehicle identification code is LA 6A 1LAP7CB400117, and the engine number is 1412G02096. It belongs to the vehicle type published in the Announcement of Vehicle Manufacturers and Products announced by the National Development and Reform Commission, and the vehicle type announcement number is 20110310000740. The first registration date of this vehicle is October 26th, 2012. The registration authority is the Traffic Police Detachment of Zhengzhou Public Security Bureau, Henan Province. The vehicle registration owner is Henan Centrino Automobile Travel Service Co., Ltd. (hereinafter referred to as Centrino Company), with 57 passengers on board, and the use nature is tourist passenger transport. The inspection is valid until April 30, 2018, and the motor vehicle status: normal. 63 historical violations have been dealt with. Insurance situation: Sunshine Insurance Company has insured compulsory insurance, car damage insurance, spontaneous combustion insurance, glass insurance, three liability insurance (2 million), passenger liability insurance on board (56 million per accident), and passenger liability insurance on board (1 million).

The actual owners of Yu AE4555 large ordinary bus are Cui Ying (male, 54 years old, ID number: 34212419640117511, No.15 Cuilou Natural Village, Sanli Administrative Village, Xiyang Town, Guoyang County, Anhui Province) and Zhang Huilei (male, 34 years old, ID number: 341223198408190516, Chengxi Town, Guoyang County, Anhui Province). After buying a car, it signed an operation contract with Centrino Company on October 22, 2012. The vehicle was registered under the name of Centrino Company, and Centrino Company handled the operation procedures and unified management, and collected management fees every month. Later, Zhang Huilei privately sold part of his shares in the car to Ding Peifeng, liuyong and Liu Xicheng. On August 6, 2015, Cui Ying and Zhang Huilei signed a joint venture agreement with Huangyan Luqiao Liushi Team (hereinafter referred to as the Team, which is described in detail below). After the agreement is signed, the original owner will no longer participate in the vehicle operation. On May 1, 2016, Feng Yong (male, ID number: 341224197406029878, 132-9-23 Mengfu Road, Chengguan Town, Mengcheng County, Anhui Province) signed a contract agreement with the motorcade. At the time of the incident, the actual control operator of Yu AE4555 bus was Feng Yong.　

On October 26th, 2012, the vehicle was evaluated in terms of vehicle technical grade, with the type grade being large and the technical grade being first grade. Meet the standards for operating inter-provincial and inter-city non-fixed-line tourist passenger transport. On November 5, 2012, the vehicle handled the Business License of Henan Province Road Non-alignment Tourist Passenger Transport Area, with the license number: Yu Tourist Passenger Transport Xuzi 0011250; On November 30, 2012, the vehicle was issued with a Road Transport Certificate, the number of which was Zheng Zi 410101029623. Business scope: inter-provincial chartered passenger transport, inter-city chartered passenger transport, inter-county chartered passenger transport and intra-county chartered passenger transport.

After verification, the registration, inspection and insurance of the vehicle meet the requirements; The road transport license is legal and valid.

2.Su G391E8 minibus: The model of this car is Honda DHW6483T5ASE, the date of production is December 8, 2017, the vehicle identification code is LVHTG5834J5010239, and the engine number is 1028307. The vehicle model published in the Announcement of Vehicle Manufacturers and Products announced by the National Development and Reform Commission was first registered on January 10, 2018. The registration authority was the Traffic Police Detachment of Lianyungang Public Security Bureau, Jiangsu Province. The registered owner was Chen Haoran, and the use nature was non-operating, with 5 people on board. The inspection is valid until January 31, 2020, and the motor vehicle status is illegal and unprocessed (there are two illegal records, 1 case has been processed and the other case has not been processed). Insurance situation: People’s Property Insurance Company covers compulsory insurance and three liability insurance (1 million), and the liability insurance for personnel on board is limited to 10,000 (5 persons) per seat.

　After verification, the registration, inspection and insurance of the vehicle meet the requirements.

(two) the driver of the accident vehicle

1.The driver of Yu AE4555 large ordinary bus: Shao Dandan, male, 33 years old, born on June 1, 1985, ID number: 341223198506010734, household registration address: No.66, Huang Zhuang Natural Village, Huang Zhuang Administrative Village, Chengdong Street, Guoyang County, Anhui Province, driver’s license number: 341223198506010734, file number: 344. The issuing authority is the Traffic Police Detachment of Bozhou Public Security Bureau, Anhui Province. On November 15th, 2004, it applied for E-license for the first time. On June 7th, 2007, it added the quasi-driving model to B2E, and on May 20th, 2014, it added the quasi-driving model to A1E. The verification is valid until November 15, 2020. The driver’s license is in normal condition, and there are 13 historical illegal records, all of which have been processed.

Shao Dandan’s qualification category is road passenger and general cargo transport driver, with the qualification certificate number of 3416010030013013181, the initial issuance date: June 22, 2007, the issuance date after renewal: April 13, 2013, and the validity period: April 13, 2019.　

After verification, the driver Shao Dandan’s driver’s license application and verification is legal and valid; The road transport qualification certificate is legal and valid. Suffered minor injuries in the accident.

2.Driver of Su G391E8 minibus: Chen Haoran, male, 30 years old, driver’s license number: 32070319880226201X, born on February 26, 1988, Liandao Town, Lianyun District, Lianyungang City, Jiangsu Province, quasi-driving model: C1, issuing authority, traffic police detachment of Lianyungang City Public Security Bureau, Jiangsu Province, and the date of first obtaining the license: March 12, 2010. The validity period of verification is March 12, 2026, and the driver’s license is normal.

After verification, the application and verification of driver Chen Haoran’s driver’s license are legal and valid. Be injured in this accident.　

(3) Accident road conditions　　

The incident road section is located at K61+250-300 of Lianhuo Expressway (No.G30). In 1998, Lianxu Expressway was established by the State Planning Commission in document No.327 [1998] and approved by document No.1603 [1998]. The Ministry of Communications approved the preliminary design in document No.640 [1998] and the State Planning Commission in document No.1636 [1998]. Lianxu Expressway is a section in Jiangsu Province, which is the national trunk line from Lianyungang to Horgos (G30). It starts from Dagang Road in Lianyungang and ends at the junction of Jiangsu and Anhui in Xuzhou City, with a total length of 236.784km and a design speed of 120 km/h. The design load of bridges and culverts is standard car-super 20 and trailer-120, and the subgrade is 28.0m wide, with four lanes in both directions, and the whole interchange is fully enclosed. The road design unit of the incident section is the First Highway Survey and Design Institute of the Ministry of Communications, the design unit of traffic safety facilities is Xi ‘an Highway Research Institute, the construction unit of traffic safety facilities is Nanjing Highway Protection Facilities Engineering Company, the supervision unit is Jiangsu Weixin Engineering Consulting Co., Ltd., and the construction unit is Jiangsu Expressway Construction Headquarters. The incident road section is located at K61+250-300, which started construction at the end of 1998 and was completed in October 2001. On November 18-19, 2001, Jiangsu Provincial Communications Department and Jiangsu Provincial Expressway Command organized the handover acceptance, and the project quality grade was excellent. After acceptance, it was delivered to Jiangsu Lianxu Expressway Co., Ltd. for operation.It passed the completion acceptance in November 2003. Since the operation of Lianxu Expressway, Jiangsu Lianxu Expressway Co., Ltd. has invested sufficient maintenance funds every year in accordance with the maintenance technical specifications and related systems, actively adopted advanced technology to carry out preventive and periodic maintenance of roads, and maintained the MQI value of highways at an excellent level all the year round.

The plane alignment of the incident road section is designed as a straight line, with longitudinal slope of 0.8% (uphill), transverse slope of 2%, asphalt concrete pavement, The pavement cross-section layout is: 0.75m (marginal strip)+3.5m (emergency lane)+3.75m (second lane)+3.75m (first lane)+0.75m (median)+3.5m (median)+0.75m (first lane). M (emergency lane)+0.75m (marginal strip), with a total subgrade width of 28m. There are white single solid lines at the emergency lane and the median, and white dotted lines between the first lane and the second lane. Corrugated beam guardrails are set on both sides of the median, and Chinese juniper is planted in the middle. The guardrail in the incident section was built during the construction period, and the construction time was May 2001. According to the recent inspection report on the pavement technical condition of Lianxu Expressway, the pavement performance index (PQI) of this section is maintained at an excellent level.

After verification, the technical indicators of the incident road section meet the requirements of relevant standards and specifications; There have been no road traffic accidents in this section in the past three years, and no safety hazards have been found on this road.

(4) Weather conditions at the time of the incident

When the accident happened, the weather at the scene was light rain. According to the meteorological certificate of Lianyungang Meteorological Bureau, from 15: 00 to 17: 00 on April 12, the maximum wind speed was 3.4 m/s, and the occurrence time was 16: 00; The rainfall from 15: 00 to 17: 00 is 6.5 mm, of which the rainfall from 15: 00 to 16: 00 is 3.5 mm and the rainfall from 16: 00 to 17: 00 is 3.0 mm..　

Upon verification, the road surface was wet, and there was no water, no fog and no obstructions that affected the line of sight.　

(five) the accident related units.

　1.Centrino company. The company was established on February 6, 2007, with the industrial and commercial registration number of 410105100081185, the enterprise credit code of 91410103799151706P, the company type is a limited liability company (invested or controlled by natural persons), the registration authority is Zhengzhou Erqi District Administration for Industry and Commerce and Bureau of Quality and Technical Supervision, and the enterprise address is Room 1401, 14th floor, Block B, olive city Metropolitan Plaza, Erqi District, Zhengzhou City. Legal representative: Zhang Jing (female, ID number: 410103198301227004, No.29, Building 3, Yard 6, Min ‘an Road, Erqi District, Zhengzhou City), business scope: chartered passenger transport, tourist passenger information consultation, car rental, business period: February 6, 2007 to February 5, 2022. In June 2011, Feng Xianfeng (female, ID number: 410103195910231021, domicile: Room 189, 20th floor, Unit 2, Building 1, Fu Garden Community, University South Road, Erqi District, Zhengzhou City, and current address: Room 102, Unit 2, Building 7, No.158, Southeast Road, Guancheng District, Zhengzhou City) and Zheng Yueming (male, ID number: 4123231966. Domicile: No.29, Building 3, Courtyard 6, Min ‘an Road, Erqi District, Zhengzhou City, and current address: Donghu, Floor 6, Unit 2, Building 4, No.158, Chengdong South Road, Guanchenghui District, Zhengzhou City) each invested 500,000 yuan to acquire all the shares of the company, and the legal representative is Feng Xianfeng (Feng Xianfeng and Zheng Yueming are half-sisters).At the beginning of 2016, the legal representative was changed to his daughter Zhang Jing, and Zheng Yueming was the leader and general manager of the safety production leading group of Centrino Company, who was fully responsible for the daily management and operation of the company.

2.Anhui Mengcheng "Luqiao Huangyan Liushi motorcade". According to verification, the motorcade was not registered in the industrial and commercial department. In 2014, it was composed of the vehicle operators of Luyi (Zhoukou, Henan)-Luqiao (Taizhou, Zhejiang)-Liushi (Yueqing, Zhejiang)-Fuding (Ningde, Fujian) line and Guoyang (Bozhou, Anhui)-Huangyan (Taizhou, Zhejiang)-Shishi (Quanzhou, Fujian) line through consultation, and Wang Bo (male, ID number: 3416222) who operated vehicles on both lines was selected. The office is located in Mengcheng County, Anhui Province. There are 25 buses in the convoy, including 7 buses, including Anhui S59743 (blue brand), Anhui SWW101 (blue brand), Anhui SM9101 (blue brand), Shanghai C40608 (yellow card), Shanghai C41345 (yellow card), Zhejiang J3702H (blue brand) and Zhejiang JH739Y (blue brand). The remaining 18 buses are large buses, which are registered for road passenger transport and tourist passenger transport. See the table below for relevant information:

2016 May 1, 2008 Feng Yong signed a contract agreement with the motorcade, and the motorcade handed over 25 buses, including accident cars, to Feng Yong for operation at a price of 6.6 million yuan per year. The contract period was from May 1, 2016 to April 30, 2019. At the time of the incident, the actual control operator of Yu AE4555 bus was Feng Yong, and Feng Yong hired Fu Dayong (male, ID number: 341224197512033010, No.93-1, Zhongxin Street, Shuangjian Town, Mengcheng County, Anhui Province), one of the shareholders, Feng Li (male, ID number: 34122319740501116), to be in charge of vehicle and driver scheduling.

Second,The accident process and emergency treatment.

(1) The course of the accident

2018 April 10, 2008 fiveAt about 30: 00, Shao Dandan got the passenger car license plate numbered "Yuyunbaozi 0265873" from the office of Feng Yong, and the destination was "Zhengzhou-Liushi" passing through Xuzhou, Lianyungang, Rizhao, Weifang, Guoyang, Mengcheng and other places (afterwards, it was found that the license plate of the passenger car was forged, which was purchased by Feng Li through the social "scalper" Li Dengchao in Guoyang County, Anhui Province with 50 yuan money, after the incident. Drive Yu AE4555 bus to meet people at Mengdie Square in Mengcheng County, Anhui Province, and prepare to visit Shandong Shenghong Pharmaceutical Technology Co., Ltd. (hereinafter referred to as Shenghong Company) in Weifang, Shandong Province.

sevenAt about 30: 00, Shao Dandan drove Yu AE4555 bus (with 57 passengers on board) and a group of 45 people including Zhang Kun (male, ID number: 341224197811056896, No.72, lingshan village Zhangzhuang, Xiaojian Town, Mengcheng County, Anhui Province, franchisee and salesman of Shenghong Company Anhui Branch, operating Xiaojian Town Pharmacy in Mengcheng County), and left for Mengdie Square. At about 16: 30 on the same day, I arrived at Shenghong Medical Company and stopped for about 1 hour. Then I drove to Super Eight Hotel on Shengli Road to check in. After that, I drove to a restaurant 2 kilometers away and parked my car in the hotel parking lot.

four November 11 th sevenAt about 10: 00, Shao Dandan took a taxi to the hotel parking lot, drove to the hotel to take 45 people from Zhang Kun and his party to visit Shenghong Company, and returned to the restaurant for dinner before 14: 00, and then drove the passengers to the hotel for rest. At about 18 o’clock, I drove the passengers to the hotel for dinner. After that, I sent the passengers back to the hotel to stay, and then I sent the car to the hotel parking lot.

four December 12 sevenAt about 10: 00, Shao Dandan drove to pick up passengers, entered Qingyin Expressway from Weifang West, passed G15 Shenhai Expressway, and arrived at Lianyungang Liandao Scenic Area at about 13: 00. During the period, Shao Dandan ate instant noodles on the bus. At 14: 30, he drove the bus from Liandao, then drove into G30 Lianhuo Expressway, rested in Jinping Mountain Service Area, and the passengers ate for about 20 minutes. At 15: 30, he started from the service area and drove from east to west along Lianhuo Expressway to Xuzhou. At 15: 50, he arrived at K61+250-300. Shao Dandan drove Yu AE4555 Jinlong bus through the central guardrail and collided with Su G391E8 Honda minibus (with 4 passengers) driven by Chen Haoran, Liandao Town, Lianyun District, Lianyungang City from west to east, resulting in 8 deaths (6 of them died on the way to the hospital, 2 died after being rescued on the same day and the next day respectively), 1 serious injury and 36 minor injuries.

(2) Emergency handling situation

1.Alarm and response

2018 April 12, 2008 16At 10: 00, the 110 Command Center of Lianyungang Public Security Bureau received an alarm that a bus collided with an off-road vehicle after crossing the central guardrail at 61 km+300 meters from west to east of Lianxu Expressway. After receiving the report, the 110 Command Center quickly assigned the Fourth High-speed Brigade of the Traffic Police Detachment of the Municipal Public Security Bureau and the Traffic Police Brigade of Donghai County Public Security Bureau to rush to the scene for disposal, and informed the fire and 120 emergency departments to rush to the scene to participate in the rescue. At about 16: 20, the traffic police brigade of Donghai County Public Security Bureau and the high-speed four brigades of the traffic police detachment arrived at the scene of the accident, carried out rescue and disposal work and immediately reported to their superiors.

The Party committees and governments of Lianyungang City and Donghai County immediately launched emergency response, and quickly organized relevant personnel from public security, fire protection, safety supervision, transportation, medical care and other departments to rush to the scene to carry out on-site rescue and after-care work in time. The heads of the Municipal Public Security Bureau, the Municipal Safety Supervision Bureau, the Municipal Transportation Administration and other units quickly rushed to the scene to organize and command, and performed their duties, cooperated with each other, and worked quickly and effectively.

Lianyungang Public Security Bureau quickly launched an emergency plan, and set up a disposal leading group with Wang Yongsheng, deputy mayor and public security bureau chief, as the team leader, and other party committee members as the deputy team leaders. Seven working groups, including comprehensive coordination, accident investigation, public opinion guidance and control, after-care disposal, legal guidance, emergency response and logistics support, were set up to carry out rescue work at the scene of the accident.

Li Weixin, deputy director of the Provincial Safety Supervision Bureau, Wang Wen and Zhu Zixing, deputy heads of the Traffic Police Corps of the Provincial Public Security Department, and other leaders rushed to the scene of the accident to direct rescue and guide the aftermath. Wang Bingbing, researcher and deputy director of the Accident Department of the Traffic Management Bureau of the Ministry of Public Security, led relevant experts from the Traffic Management Science Research Institute of the Ministry of Public Security to come to the company overnight to guide the accident handling work.

four March 13 Zhao Ruihua, deputy director of the Second Department of Safety Supervision of the Ministry of Emergency Management, and Shi Yong, deputy director of the Traffic Management Bureau of the Ministry of Public Security, personally went to Lianyungang to convene a meeting to deploy accident investigation and handling. Pei Jun, deputy director of the Provincial Public Security Department, came to Lianyungang to guide the accident handling. On April 16th, Zhang Jianjun, Director of Technical Management Office of Highway Bureau of Ministry of Transport, and his team of four people inspected the accident vehicles and guardrail, and then re-inspected the road and guardrail at the site.

2.Emergency treatment at the scene of the accident

After the accident, the leaders of Lianyungang City and Donghai County Party Committee and County Government led the heads of relevant departments to rush to the scene at the first time to direct the accident handling and rescue work. Public security, transportation, fire protection, 120 first aid, road administration and other departments quickly carried out rescue of the wounded, site investigation, investigation and evidence collection, vehicle rescue, site cleaning and other work, and the accident site was removed and traffic resumed at 19: 00 on the same day. During the period, the traffic police department dispatched 8 police cars and more than 60 police officers, the fire department dispatched 2 fire rescue vehicles and more than 20 firefighters, the high-speed company dispatched more than 40 road administration, troubleshooting and maintenance personnel, and the 120 emergency departments at the city and county levels dispatched 10 ambulances. The traffic police department temporarily requisitioned two civilian cranes to participate in the rescue.　

3.Medical treatment situation

After the accident, the medical departments at Lianyungang City and Donghai County immediately opened a green channel for the medical treatment of the injured in traffic accidents, and spared no effort to treat the injured. The provincial public security department coordinated the relevant medical institutions in the province to immediately send experts to Lianyungang to participate in the rescue work, and all the injured people were treated promptly and effectively. At present, except for 5 people who are still being treated in the hospital, all others have been cured and discharged.

4.Treatment of aftermath

After the accident, the after-care team quickly carried out compensation for traffic accident damage. On the morning of April 13th, in conjunction with the municipal insurance industry association, we discussed the aftermath of accident claims with the responsible persons of Sunshine Insurance Company, Zhejiang Branch and Hangzhou Branch, and issued a notice of payment (advance payment) for road traffic accident rescue expenses to Sunshine Insurance Hangzhou Branch. On the afternoon of 13th, Sunshine Insurance Company paid 3 million yuan in advance to compensate for the advance payment. On April 14th, Centrino Company paid 3.5 million yuan in rescue expenses in advance. On April 24th, Feng Yong paid 600,000 yuan for the rescue. On April 17th, the director of Mengcheng County Judicial Bureau and his party arrived in Donghai County to assist in compensation mediation. On April 18th, a group of eight people from the accident aftermath compensation group of Sunshine Insurance Company Hangzhou Branch arrived in Lianyungang again to participate in accident compensation mediation. Up to now, all the bodies of the dead have been cremated, and all the dead have reached a compensation agreement except one who has gone through legal proceedings. All the injured have ended mediation except five who are still being treated in the hospital and three who have not been identified for injuries.

Iii. Investigation and evidence collection

(a) the trace of the accident

The scene of the accident is the original scene, involving two vehicles. Among them, the head of Yu AE4555 large-scale ordinary bus turns to the left side of the car body in the right lane from Xuzhou to Lianyungang. The rear wheel is 4 meters away from the south edge guardrail of the road, the front wheel is 3.8 meters away from the south edge guardrail of the road, 4 meters away from the east-west direction of K61+ 300M road mileage pile, and 21.8 meters away from the east-west direction of the right rear wheel of Su G391E8 small bus. The right rear wheel of the minibus is 5.1m away from the south edge guardrail of the road, and the right front wheel is 4.2m away from the south edge guardrail of the road.

(II) Vehicle damage

The front windshield of AE4555 large ordinary passenger car in Henan province is broken and scattered, the whole right side of the cab is pressed and deformed to the left side of the car body, the surface glass fiber decorative board is broken and defective, and scratches and green plants are seen at the exposed steel frame of the internal steel frame. Right front door is missing. The skin in the middle of the front bumper is missing, and the front metal guardrail is depressed and deformed inward. The window glass on the right side of the vehicle is broken and missing, and a large area of falling scratches is seen at the position above 220cm from the ground at the right rear part of the vehicle body, and the whole right rear part is extruded and deformed to the left side of the vehicle body. On the left side of the car body, a large number of scratches were found, and the window glass was partially broken and missing. There are two parallel extrusion deformation marks at the rear of the roof, flaky scratch marks at the front of the roof, and black substance adhesion.

The roof of Su G391E8 small ordinary passenger car is bent and deformed downwards, and the airbag on board is open. A large amount of blood and fragments of the front windshield of Henan AE4555 large ordinary bus were scattered inside the cab. A large number of scratches were found on the engine compartment cover, and the red rust substance adhered and the glass fragments of the large ordinary passenger car window were scattered. The left front fender of the car body was extruded and folded from front to back. The front bumper skin is missing as a whole, and there are longitudinal scratches and glass fiber-like substances embedded in the radiator within the range of 50cm -90cm from the ground. The right rear tire lost pressure and its metal hub was broken.

(3) Blood tests

According to the appraisal report [2018] No.865, no ethanol component was detected in Shao Dandan’s blood. According to the appraisal report [2018] No.866, no ethanol component was detected in Chen Haoran’s blood. According to the identification report of Lian Gong Wu Jian (Drugs) Zi [2018] No.39, no amphetamine, methamphetamine, MDMA, ketamine, morphine and monoacetylmorphine were detected in Shao Dandan’s urine. According to the identification report [2018] No.40, no amphetamine, methamphetamine, MDMA, ketamine, morphine and monoacetylmorphine were detected in the urine of Chen Haoran.

(4) Vehicle inspection

Appraised by dmv, Traffic Police Detachment of Lianyungang Public Security Bureau:

Accident car Yu AE4555: (1) Vehicle appearance: the outline size (length× width× height) and wheelbase, brand model, body color, axle number, tyre size and the rated number of passengers are in conformity with the certificate; (2) The number of passenger doors of the accident large ordinary bus is 2, and there are 4 emergency windows (three glasses are damaged, one glass is intact, and emergency exit signs are affixed, and there are 3 safety hammers, but one is missing), 2 escape exits on the roof, 1 warning sign, installation of driving recorder, no nameplate of the finished vehicle and no fire extinguisher; (3) Braking and steering: the accident vehicle did not see the front wheel disc brake and was equipped with ABS. Due to the accident, the vehicle was seriously damaged, the steering tie rod was deformed, the four-wheel anti-lock braking device was disassembled, and the engine could not work normally and there was no air pressure, so the braking and steering performance could not be tested; (4) The vehicle identification code needs to be contacted with the vehicle management office where the vehicle is registered to check its authenticity (note: it is verified to be true later); (5) There are 57 registered seats for buses, 57 damaged vehicles and 57 seat belts, but some seat belts are found to be damaged during inspection; (6) The tire under inspection has no retreaded tire and is seriously worn. The tire crown pattern is 1.1mm for the left front wheel, 1.0mm for the right front wheel, 0.3mm for the left rear tire and 0.4mm for the right rear tire. The tread depth of steering wheel should be greater than or equal to 3.2mm, and the tread depth of other tires should be greater than or equal to 1.6mm, resulting in serious tire wear.Does not meet the "technical conditions for motor vehicle operation safety"; The right front tire is broken, which belongs to impact damage.

The accident of Su G391E8 minibus caused serious damage to steering system, braking system, running system and other parts, and the performance of steering system and braking system could not be tested.

(5) Trace inspection.

According to the appraisal opinion No.104 [2018] of Zhengda Sijian Center, in this accident, the right front part of Yu AE4555 blue Jinlong bus driven by Shao Dandan came into contact with the left front part of Su G391E8 Honda minibus driven by Chen Haoran. At the time of the accident, the Yu AE4555 blue Jinlong bus driven by Shao Dandan did not come into direct contact with vehicles other than the Su G391E8 Honda minibus driven by Chen Haoran.

(VI) Driving data of AE4555 large ordinary bus in Henan.

The memory card data of AE4555, a large ordinary bus, was read in the road traffic accident appraisal by the Institute of Traffic Management Science of the Ministry of Public Security. The time period of driving record on the day of the accident was: (1) 00: 00-08: 31: 16 on April 12, 2018. Last location: Rongwei Expressway in Weifang. Final speed: 77 km/h. (2) April 12, 2018, 11:09:14-11:29:0. Last location: Rizhao service area of G15 Shenhai Expressway. No driving data was found on the day of the incident: (3) 08: 31: 17—11: 09: 14 on the 12th; (4) 11: 29: 03 on the 12th—when the accident happened.

Fourth,Cause and nature of the accident

(A) the direct cause

1.Shao Dandan, a bus driver, is the direct cause of the accident when he drives a vehicle whose tires are worn out and do not meet the technical standards in rainy days.

2018 April 19, 2008 The No.4 Brigade of the Traffic Police Detachment of Lianyungang Public Security Bureau made a road traffic accident confirmation letter [2018] No.001, and Shao Dandan drove a motor vehicle whose parts did not meet the technical standards on the road and did not drive safely, respectively violating Article 21 of the Road Traffic Safety Law of the People’s Republic of China: "Before driving a motor vehicle on the road, the driver should carefully check the safety and technical performance of the motor vehicle; Do not drive a motor vehicle with safety facilities or parts that do not meet technical standards and other safety hazards. " Paragraph 1 of Article 22: "Motor vehicle drivers shall abide by the provisions of laws and regulations on road traffic safety, and drive safely and in a civilized manner in accordance with operational norms." The provisions of. Take full responsibility for the accident.

2.Shao Dandan failed to fulfill the obligation of safety reminder. At the time of the accident, most passengers in the bus didn’t wear seat belts, and the driver didn’t remind them according to the regulations, which caused many people to be thrown out of the car after collision, which aggravated the consequences of accident casualties.

(2) Indirect causes

1.Centrino Company did not strictly perform the main responsibility of safety production, and did not seriously educate and urge employees to strictly implement the company’s rules and regulations and operating procedures, which led to Shao Dandan’s improper operation when driving in rainy days; Safety production management is not in place, and effective measures have not been taken to check the AE4555 bus in Henan regularly according to the company’s regulations, and the hidden trouble of serious tire tread wear has not been rectified during the accident; We failed to take effective measures in time to solve the problem that the vehicle is sometimes off-line during the dynamic monitoring.

2.Zhengzhou Road Transportation Administration failed to supervise Centrino Company’s enterprises, and neglected Centrino Company’s failure to seriously implement the company’s regular inspection system for passenger vehicles. Supervise Centrino Company to implement the dynamic monitoring management system is not in place.

3.The third brigade of the traffic police detachment of Zhengzhou Public Security Bureau is not sure about the operation of accident vehicles of Centrino Company within its jurisdiction, and its supervision is not in place.

(3) Nature of the accident

After investigation, it was found that the "4.12" major road traffic accident in Lianyungang was a road traffic liability accident.

Five, the handling of the accident related responsible personnel and responsible units and suggestions.

(a) the judicial organs have taken measures.

1.Shao Dandan, the driver of the accident vehicle, was criminally detained by Lianyun Public Security Bureau on April 13, 2018 on suspicion of traffic accident. He was arrested by Lianyun District Procuratorate on April 20 and is now detained in the city detention center.

2.Zheng Yueming, Zheng Yueming, the shareholder and general manager of Centrino Company and the leader of the leading group for safety production, was criminally detained by Donghai County Public Security Bureau on April 14, 2018 and released on bail pending trial on April 23.

3.Feng Yong, the contractor of Yu AE4555 large ordinary bus, was criminally detained by Donghai County Public Security Bureau on April 21, 2018, and released on bail pending trial on April 25.

4.Fu Dayong, the dispatcher of Yu AE4555 large ordinary bus, was criminally detained by Donghai County Public Security Bureau on April 21, 2018 on suspicion of major accident, and was released on bail on April 25.

(two) it is recommended to give disciplinary action to the party and government.

1.Zhang Zhihua, party member of the Communist Party of China, is the head of the Passenger Transport Department of Zhengzhou Road Transportation Administration, responsible for the management of the city’s road passenger transport industry, and has the supervisory responsibility for the passenger transport department to carry out the supervision of the tourism passenger transport industry. Failure to effectively supervise the work of department personnel. It is recommended to give a serious warning.

2.Zhou Bingjie, party member of the Communist Party of China, deputy detachment leader of the inspection detachment of Zhengzhou Road Transportation Administration Bureau, was transferred to the Passenger Transport Department due to work needs, and was responsible for the management of the license plates of tourist passenger vehicles in the city. He was responsible for supervising the enterprises’ failure to apply for license plates in accordance with relevant regulations and failed to effectively supervise the enterprises’ receipt and use of license plates. It is recommended to give administrative warning.

3.Zhang Xiaofeng, party member, member of the Passenger Transport Section of Zhengzhou Road Transportation Administration, is responsible for the license management of tourist passenger transport enterprises and operating vehicles in the city, and is responsible for the supervision of enterprises that fail to strictly carry out the management of tourist passenger transport industry according to relevant regulations. In daily management, the company failed to effectively supervise the safety management of operating vehicles. It is recommended to give administrative warning.

4.Zhang Zhigen, party member of the Communist Party of China, is a member of the Passenger Transport Section of Zhengzhou Road Transportation Administration. He is responsible for the safety inspection of tourist passenger transport enterprises in the city and is responsible for the supervision of the failure to effectively carry out the safety inspection of tourist passenger transport according to regulations. The inspection of tourist passenger transport enterprises in the city was not detailed and comprehensive, and it failed to effectively supervise enterprises to strictly carry out the management of tourist passenger transport industry in accordance with relevant regulations. It is recommended to give administrative warning.

5.Wang Jinzhu, party member of the Communist Party of China and the captain of the third brigade of the traffic police detachment of Zhengzhou Public Security Bureau, failed to deploy and supervise the work of superiors, resulting in weak links in the supervision of key vehicles. It is recommended to give administrative warning.

6.Li Xun, party member of the Communist Party of China, deputy director of the supervision office of key objects of the third brigade of the traffic police detachment of Zhengzhou Public Security Bureau, was not sure about the operation of accident vehicles and did not supervise them properly. Suggest admonishing conversation, informed criticism.

7.Wang Kai, party member of the Communist Party of China, and the police in the supervision office of the third brigade of the traffic police detachment of Zhengzhou Public Security Bureau, are not sure about the operation of the accident vehicles and the supervision is not in place. Suggest admonishing conversation, informed criticism.

(3) Administrative punishment and accountability suggestions

1.It is suggested that the safety production supervision and management departments and transportation departments of Zhengzhou City, Henan Province should investigate Centrino Company and its related responsible persons according to relevant laws and regulations.

2.It is suggested that the relevant departments of Anhui, Zhejiang and Henan provinces implement the territorial supervision responsibility for the passenger vehicles of "Luqiao Huangyan Liushi Team" in Mengcheng, Anhui Province, and urge relevant enterprises to fully implement the main responsibility of enterprise safety production.

3.It is suggested that the public security organs in Mengcheng, Anhui Province should further investigate and deal with Li Dengchao, who is suspected of forging a chartered bus line card.

Six, accident prevention and rectification measures

(A) around the accident prevention, take measures simultaneously, and quickly carry out special rectification.

After the accident, Lianyungang public security traffic management department attached great importance to it, and immediately launched a special campaign for the rectification of expressway buses for half a year from April 13 with the departments of highway law enforcement, transportation and road companies. First, strengthen organizational leadership and earnestly formulate plans. A special meeting was held overnight to study and deploy the rectification work, and five expressway companies including Jiangsu Lianxu and 19 expressway traffic police brigades and public security checkpoints were quickly convened to comprehensively carry out the special rectification of expressway traffic and passenger transport order in the city. The second is to strictly control the road surface and strengthen cooperation. The leaders of the municipal bureau and detachment led the team to go on duty to enforce the law, board the car for inspection and carry out safety publicity. Public security checkpoints implement a 24-hour service mode, relying on the inspection and control system to inspect inter-provincial tourist chartered cars, and strictly investigate traffic violations such as "three overload and one fatigue" and not wearing seat belts; The high-speed brigade takes toll stations and service areas as positions to inspect the performance and operating qualifications of fixed-line vehicles in its jurisdiction. Strengthen cooperation with road companies, road administration and other departments, and carry out "one road, three cars" joint duty law enforcement work. The third is to strictly investigate hidden dangers and plug security loopholes. The detachment held an accident prevention meeting with five expressway companies to form a meeting summary to clarify the investigation scope, content, responsible unit and rectification period of expressway traffic safety hazards, and eliminate safety hazards in time. The fourth is to use sufficient legal means to ensure the remediation effect. At the same time, the penalty points for bus traffic violations shall be copied to the transportation management department where the vehicle registration is located. For the illegal operation of road passenger vehicles,Handed over to the road law enforcement and traffic management departments for handling. The fifth is to strengthen publicity and education and raise the awareness of traffic safety of the whole people. Since the rectification activities, a total of 5,950 buses have been inspected and registered, 1,450 traffic violations of various passenger vehicles have been investigated, 15,000 drivers have been reminded to wear seat belts, more than 40,000 traffic safety reminder cards have been issued, 6 passenger transport enterprises have been interviewed, and 76 rectification notices have been issued.

(two) improve the safety production system, conscientiously implement the main responsibility of production safety.

It is suggested that Henan Xunchi Automobile Travel Service Co., Ltd. should further implement the main responsibility of safety production, establish and improve various safety production systems, effectively strengthen the safety management of its vehicles and drivers, and ensure that all safety production rules and regulations are in place; It is necessary to strengthen the safety assessment training and education for all drivers, ensure that employees have the necessary knowledge of safety production, be familiar with relevant safety production rules and regulations and safety operation skills, and enhance the safety awareness of employees and the emergency handling ability of emergencies; It is necessary to use the satellite positioning monitoring platform to monitor the whole process of the company’s passenger vehicle operation, and it is not allowed to arrange the operation of passenger vehicles that can’t stay online when the satellite positioning device fails.

(C) to further enhance the awareness of road traffic safety red line and sense of responsibility.

It is suggested that Zhengzhou road transport management department should give full play to its functions and take effective measures, further urge road transport enterprises, effectively enhance the awareness of red line, strictly implement the main responsibility of safety production, strictly abide by and implement the laws and regulations on safety production, strengthen safety production education and training, improve workers’ safety awareness, and promptly investigate and control hidden dangers of accidents; It is necessary to urge and guide enterprises to implement the main responsibility of dynamic monitoring, strengthen dynamic monitoring, and take effective measures to curb illegal business practices.

(D) Take multiple measures to strengthen the daily supervision of road transport enterprises in the area.

It is suggested that the public security traffic management department of Zhengzhou City should take multiple measures to strengthen the daily supervision of road transport enterprises in its jurisdiction. First, we must strictly implement the supervision system and urge enterprises to implement the main responsibility. By holding regular safety meetings, signing safety responsibility letters, reporting the safety situation, analyzing traffic accident cases and other effective ways, we will implement various supervision systems and urge enterprises to implement the main responsibility. Second, we must conscientiously implement regulatory responsibilities and strengthen the implementation of measures. It is necessary to give full play to the current effective measures such as online inspection, in-depth supervision and inspection of enterprises, problem notification, problem copying, and timely interviews, further implement the requirements of the basic information management work norms of public security traffic management business, and do a detailed supervision of the source. Third, we must earnestly urge the problem to be rectified to ensure effective results. While signing the safety responsibility book, establishing and perfecting the account, holding the regular safety meeting, and issuing the rectification notice, we should stick to the problems found, and urge the problems to be rectified in place without leaving any dead ends.

(5) Promote the work of "clearing" potential safety hazards and vigorously carry out special rectification.

It is suggested that Zhengzhou road transport management, public security traffic management and other relevant departments should conscientiously perform their supervisory responsibilities, comprehensively investigate the problems existing in enterprises under their jurisdiction, urge enterprises to implement the main responsibility, and vigorously promote the work of "clearing" safety hazards, especially the safety hazards of "two passengers and one danger" vehicles and drivers. At the same time, we will carry out joint special rectification, focusing on checking the implementation of dynamic monitoring measures and daily safety education and training of tourist passenger transport enterprises, checking the regular inspection and daily maintenance of vehicles, checking the driver’s driving qualification and professional qualification, checking the procedures for chartering tourist buses, urging enterprises to check the integrity of passenger tires and seat belts, and implementing the passenger safety notification system. Tourist buses and drivers who do not have the corresponding qualifications will be banned; Tourist passenger transport enterprises that fail to perform their safety management duties will be suspended for rectification; All tourist buses whose safety performance does not meet the standard or whose GPS monitoring system is not installed will stop operating; Those who violate the examination and approval route and issue blank chartered cars will be severely punished and seriously investigated for accountability. The list of vehicles and enterprises with potential safety hazards will be notified to the safety supervision departments, and a number of enterprises with outstanding potential safety hazards will be jointly interviewed and exposed, and the source education and management measures will be urged to be implemented.

(six) to strengthen publicity and guidance, and strive to develop the rules and atmosphere of safe driving.

Road transport management, public security traffic management and other departments in the relevant areas should pay attention to "4? 12 "The causes of major road traffic accidents are analyzed. Around the prevention of serious traffic accidents and tourist bus accidents, various ways are adopted to quickly set off a climax of traffic safety publicity tips and education warnings to prevent similar problems from happening. It is necessary to establish and improve the mass reporting mechanism, carry out award-winning reporting activities, fully mobilize the enthusiasm of the masses to report illegal driving and illegal operation, and widely mobilize social supervision. Guide the relevant units and personnel not to rent or take tourist buses without chartered procedures or incomplete procedures, which have potential safety hazards, and form a good atmosphere for safe driving and safe car use.

The extinction at the end of Permian 252 million years ago caused the extinction of about 81% marine species and 89% terrestrial species. The main reason is believed to be the environmental change caused by large-scale volcanic eruption, but there is still no direct evidence that environmental factors affect terrestrial ecosystems. In cooperation with foreign counterparts, researchers in China discovered the direct evidence that the destruction of the ozone layer led to the extinction of terrestrial life at the end of Permian by studying the changes of "sunscreen" content in fossil pollen grains during this period.

The research results were published online in the internationally renowned journal Science Advances on January 6, 2023.

Black shale at the end of Permian in Qubu section of southern Tibet. Photo courtesy of Nanjing Institute of Geology and Paleontology, CAS

Pollen fossils found in Permian-Triassic transitional strata in Qubu section. Photo courtesy of Nanjing Institute of Geology and Paleontology, CAS

Volcanic eruption led to mass extinction of land? There was a lack of direct evidence

The extinction event at the end of Permian was the largest extinction event in Phanerozoic. Scientists generally believe that the increase of global greenhouse gases caused by the eruption of Siberian igneous province at the end of Permian, global warming and ocean acidification may be the main causes of this extinction. However, there are still many debates about how these environmental factors affect terrestrial ecosystems.

Some palynologists have found some deformed spores and pollen in the continental Permian-Triassic transition section. It is speculated that these deformed spores or pollen may be caused by the increase of ultraviolet radiation induced by the destruction of the global ozone layer caused by halogen elements ejected from the Siberian igneous province. However, the study of abnormal spores and pollen produced in modern plants shows that the environmental background of these abnormal pollen and spores is very complicated, and drought, air pollution and plant trauma may all induce abnormal spores or pollen to be produced in plants. Therefore, the discovery of a small number of abnormal spores and pollen in the continental Permian-Triassic transition section cannot directly prove that there was an increase in ultraviolet radiation caused by the global ozone hole during the extinction at the end of Permian.

Using the content of "sunscreen" to deduce the intensity of atmospheric ultraviolet radiation

Plants need sunlight for photosynthesis to provide energy for plant growth, but at the same time, it is necessary to avoid the damage of harmful ultraviolet rays in sunlight to genetic information in plants, especially in plant reproductive cells (spores and pollen). In order to adapt to the terrestrial radiation environment, terrestrial plants have evolved some regulatory mechanisms to reduce the damage of ultraviolet rays to plants. In the germ cells of plants, this mechanism is manifested in that there are a large number of compounds-coumaric acid and ferulic acid-in the outer walls of plant spores and pollen, which are very similar in function to "sunscreen cream". These compounds can form resonance-stable phenol free radicals and resist the oxidation caused by ultraviolet rays, thus protecting fragile spores and pollen and providing guarantee for the spread and reproduction of terrestrial plants.

Modern botanists have observed that plants can automatically adjust the content of "sunscreen" on the outer wall of their germ cells according to the surrounding ultraviolet radiation environment, and these "sunscreen" can be stored in the outer wall of inert spores and pollen for a long time. Therefore, in theory, researchers can determine the content of "sunscreen" in these spores and pollen, and deduce the intensity of atmospheric ultraviolet radiation in geological history.

"Sunscreen" is difficult to digest and has low nutrition, or leads to the extinction of insects.

According to Liu Feng, a researcher at Nanjing Institute of Geology and Paleontology, Chinese Academy of Sciences, the research team quantitatively measured coumaric acid and ferulic acid in 1011 pollen grains from Permian-Triassic transition section in southern Tibet, China. Through the big data analysis of infrared spectra produced by these pollen, the research team found that during the extinction at the end of Permian, the contents of coumaric acid and ferulic acid in the outer wall of pollen in the stratum were significantly higher than those in fossil pollen before and after extinction, which directly proved that there was an increase in global ultraviolet radiation during the extinction at the end of Permian.

The increase of ultraviolet radiation in the air has a far-reaching impact on the whole terrestrial ecosystem. Because ultraviolet rays not only have a strong killing effect on plant germ cells, but also cause damage to plant mesophyll cells. In order to resist the damage of ultraviolet rays to mesophyll cells, plants will synthesize lutein, coumaric acid and ferulic acid in their leaves, which will reduce the synthesis of chlorophyll accordingly, leading to the weakening of photosynthesis of plants, which will further weaken the absorption capacity of plants for greenhouse gases, further aggravating the global greenhouse gas increase caused by volcanic eruption at the end of Permian.

In addition, lutein, coumaric acid and ferulic acid in mesophyll are compounds that are difficult to digest and have low nutritional value for herbivores and insects, so the increase of ultraviolet radiation indirectly affects the terrestrial food chain, which may be the main reason for the extinction of terrestrial herbivores and insects at the end of Permian.

Beijing News reporter Zhang Lu

Editor Liu Qianxian proofreads Wu Xingfa.

　　On January 17th and 19th, two patients in Xinjiang died after taking Tangzhining Capsule (batch number "081101") labeled "Guangxi Pingnan Pharmaceutical Factory". After investigation, the "Tangzhining Capsule" that caused the patient’s death was a counterfeit drug, and the chemical component "glibenclamide" was illegally added. According to industry analysts, patients with chronic diseases such as diabetes and hypertension are huge, which has become a "gold mine" for many black-hearted drug dealers to make money. Some products advertised as pure Chinese medicine have illegally mixed western medicine ingredients, or added pharmaceutical ingredients to health foods, which is harmful to patients’ health. This has also become a focus of supervision by law enforcement departments in various places, including Guangdong Province.

　　Three chemical components are often illegally added.

　　According to reports, although the current medical level has made rapid progress, there is no major breakthrough in some difficult diseases, such as diabetes, chronic hepatitis, malignant tumors, etc., and neither traditional Chinese medicine nor western medicine can achieve a complete cure. Wei Hua, deputy director of the Department of Endocrinology, Guangdong Provincial Hospital of Traditional Chinese Medicine, said that as far as Chinese medicine is concerned, its composition is complex and its effect is mild and slow, while western medicine has continuously developed some chemical drugs which are more effective, but its side effects are relatively large. In this regard, some lawless people, taking advantage of the psychological trust of patients in traditional Chinese medicine, promote so-called pure Chinese medicine and health food, and secretly add western medicine chemical components to them, so that patients feel obvious curative effect after taking it, thus increasing sales. For example, the "Tangzhining Capsule" that went wrong this time is under the banner of Chinese patent medicine.

　　Wei Hua said that in addition to the glibenclamide added in the "Tangzhining Capsule" that went wrong this time, gliclazide and glipizide are the most commonly added hypoglycemic western medicine ingredients in those illegal products. According to the relevant regulations, chemical substances are not allowed to be added to traditional Chinese medicine. "Glibenclamide" has a strong hypoglycemic effect, and its pharmacological function is to promote insulin secretion and improve human insulin deficiency through metabolism after entering the blood. However, serious overdose may cause shock and even death.

　　It is understood that the Xinjiang Uygur Autonomous Region Institute for Drug Inspection found that the drugs taken by the deceased during his lifetime contained about 10.33 mg of "glibenclamide" per pill. "Glibenclamide" is a second-generation sulfonylurea, which has a strong hypoglycemic effect, but adults should not take more than l5 mg per day, otherwise it will endanger the life safety of users. According to the instructions of the seized drugs, the normal dosage is 9 capsules per day, which has exceeded the maximum daily dosage by 6 times.

　　You can’t add western medicine to Chinese medicine at random.

　　A person in charge of a pharmaceutical factory told reporters that the incident was not accidental, and illegal drugs, health foods, western medicines and illegal propaganda occurred from time to time. According to National Medical Products Administration, they found that it is not uncommon to add sildenafil, a component of Viagra, to the "pure Chinese medicine" for treating male sexual dysfunction, and to add thyroid hormone to diet food, which can cause hyperthyroidism, so that patients who don’t know the truth suffer from side effects of drugs for no reason. This exposes a problem: most Chinese people believe that "natural drugs" have the advantages of low toxicity and side effects, and it is inevitable that they are not alert to side effects such as dependence.

　　Wang Dahong, Secretary-General of the Market Working Committee of China Health Food Association, said that illegal addition of western medicine ingredients in traditional Chinese medicine or chemical ingredients in health food will do great harm to patients and should not be added indiscriminately. Doctors and patients use mixed Chinese and western medicines without knowing it, which can easily lead to repeated adverse drug reactions. For example, if diabetic patients don’t know that the Chinese patent medicine for lowering blood sugar is added with glibenclamide, they mistakenly think it is a "Chinese medicine with no toxic and side effects" and take it in excess, or take the western medicine for lowering blood sugar at the same time for "integrated Chinese and western medicine treatment", which will lead to overdose of hypoglycemic drugs and hypoglycemia, and even lead to blood sugar fluctuation of patients if they stop taking the medicine suddenly. Therefore, Wang Dahong said that the timely discovery and investigation of the problem "Tangzhining Capsule" has eliminated another safety hazard that harms consumers’ health, and the industry has been further eliminated.

　　Illegal addition has four characteristics.

　　Most Chinese patent medicines or health foods illegally added with western medicine ingredients have the following characteristics: First, they claim that they can cure or greatly improve certain diseases in a short period of time, and their efficacy is remarkable. Second, most drugs are sold through online advertisements, mail advertisements or health knowledge lectures. Third, most drugs or health care products are covered with legal coats. Some products are pure Chinese medicine ingredients when applying for batch number, but western medicine ingredients are added during production. Fourth, the means of addition is very secret. Knowing that the routine drug testing only examines the internal substances of drugs, criminals add western medicine ingredients to the external carriers of drugs such as capsule shell. Finally, it is suggested that consumers can check the authenticity of drugs through the official website of the State Food and Drug Administration.

　　-Medical files

　　glibenclamide

　　Glibenclamide, alias glibenclamide, Daanning, etc., is a prescription drug and must be taken under the guidance of a doctor. It is an islet hormone and a drug that affect blood sugar, and can be used to treat mild and moderate non-insulin-dependent diabetes mellitus with unsatisfactory therapeutic effect only by diet control, but the patient’s islet β cells need to have certain insulin secretion function without serious complications, such as diarrhea, nausea, headache, stomachache, liver function damage, thrombocytopenia and other adverse symptoms. If you take glibenclamide in large quantities for a long time, it will eventually lead to hypoglycemia, nephropathy and even death.

　　-Related links

　　Which drugs illegally add glibenclamide?

　　According to experts, in the drug treatment of diabetes, except insulin, most of them are oral drugs. Oral hypoglycemic drugs are usually divided into three categories: western medicine hypoglycemic drugs, pure Chinese medicine hypoglycemic drugs and Chinese and Western medicine hypoglycemic drugs. Generally, pure Chinese medicine has weak hypoglycemic effect, slow onset and high safety. Western medicine hypoglycemic agents take effect quickly and have great toxic and side effects. The combination of Chinese and western hypoglycemic agents is based on the pure traditional Chinese medicine hypoglycemic agents, and incorporates the ingredients of western medicine hypoglycemic agents, which not only has the advantages of rapid hypoglycemic effect of western medicine, but also has the advantages of high safety of traditional Chinese medicine. According to the person in charge of the provincial drug evaluation center, at present, only three kinds of oral hypoglycemic drugs, such as Yikai Xiaoke Pill, are officially registered in China. It is not the first time to illegally add glibenclamide. In 2005, the Ministry of Health investigated and dealt with two cases-

　　○ On June 15th, 2005, the Ministry of Health issued a notice, requiring all localities to investigate and deal with some batch numbers of "Ku Le Kang Capsule" produced by Liaoning Healthy Weiye Biotechnology Co., Ltd.. The Ministry of Health pointed out that when the relevant departments of Jilin Province supervised and inspected the health food "Ku Le Kang" capsules (approval number: Wei Shi Jian Zi [2002] No.0588) produced by Liaoning Health Weiye Biotechnology Co., Ltd., they found that the products marked with certain batch numbers contained chemical drugs. The capsule shells of samples with batch numbers of 20041201 (not for sale), 20040902 and 20041201 contain the chemical drug glibenclamide, and the capsule contents with batch number of 20050401 contain the chemical drug gliclazide.

　　○ On October 9, 2005, Jiangxi Food and Drug Administration announced that the law enforcement officers of Nanchang Food and Drug Administration had tested the drug "Tangbikang Jiangtangning Capsule" labeled as batch number 20050403082 produced by Jilin Shenhui Pharmaceutical Co., Ltd.: glibenclamide was illegally added to this Chinese patent medicine. (Reporter Roger Lee)

Editor: Liu Li

Recently, the China Breast Cancer Screening Standard (T/CPMA 014-2020) proposed by China National Cancer Center was published online in chinese journal of cancer prevention and treatment. The correspondent is Professor He Jie, director of National Cancer Center and academician of China Academy of Sciences.

As a common cancer, according to the latest global cancer burden data released by the International Agency for Research on Cancer (IARC) of the World Health Organization in 2020, there were 2.26 million new breast cancer cases in the world in 2020, surpassing lung cancer (2.21 million cases) for the first time, becoming the largest cancer in the world, accounting for 11.7% of new cancer cases. Among the newly diagnosed cancer patients, one in every eight is a breast cancer patient. China is a big country with breast cancer. In 2020, there will be about 420,000 new cases of breast cancer and nearly 120,000 deaths.

Screening, improving the detection rate of early breast cancer and precancerous lesions, and timely and effective treatment are important measures to improve the prognosis of breast cancer and reduce the risk of death. The standards put forward suggestions on the population, measures, results and management of breast cancer screening in China. We have sorted out the relevant contents, hoping to help you better understand the knowledge of breast cancer screening.

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Who should have breast cancer screening?

The standard suggests that people at high risk of breast cancer should be screened from the age of 40; The general risk population (all school-age women except the high-risk population) should be screened for breast cancer between 45 and 70 years old.

High-risk population

Women who meet any of the following conditions 1, 2 and 3 are at high risk of breast cancer.

1. Women with genetic family history, that is, women with any of the following: 1) First-degree relatives (mothers, daughters and sisters) have a history of breast cancer or ovarian cancer; 2) Among the second-degree relatives (aunts, grandmothers and grandmothers), two or more people suffered from breast cancer before the age of 50; 3) Among the second-degree relatives, 2 or more have ovarian cancer before the age of 50; 4) At least one first-degree relative carries a known pathogenic genetic mutation of BRCA1/2 gene, or carries a pathogenic genetic mutation of BRCA1/2 gene himself.

2. Have any of the following: 1) Age of menarche ≤12 years old; 2) menopausal age ≥55 years old; 3) Have a history of breast biopsy or surgery for benign breast diseases, or a history of atypical hyperplasia of breast (lobules or ducts) confirmed by pathology; 4) Use hormone replacement therapy of "estrogen and progesterone combination" for not less than half a year; 5) X-ray examination of breast after 45 years old suggests that the type of breast parenchyma (or breast density) is uneven compactness or compactness.

Note: Breast parenchyma types can be divided into fat type, scattered fibrous gland type, heterogeneous dense type (which may cover small masses) and dense type (which reduces the sensitivity of breast cancer detection).

3. Those who have any of the following two items: 1) No breast-feeding history or breast-feeding time less than 4 months; 2) No history of live birth (including never giving birth, abortion or stillbirth) or the age of first live birth ≥30 years old; 3) hormone replacement therapy using only "estrogen" for not less than half a year; 4) Abortion (including natural abortion and induced abortion) shall not be less than 2 times.

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How to screen?

General risk population: breast ultrasound examination should be performed every 1-2 years; If you do not have the conditions for breast ultrasound examination, you should use mammography.

High-risk population: breast ultrasound combined with mammography is performed once a year.

How to understand the screening results?

Classification of diagnostic results of mammography

The diagnostic results of mammography are usually classified by the Breast Imaging Reporting and Data System (BI-RADS), which is formulated by American Radiological Society (ACR) and widely used internationally.

1. BI-RADS 0: The existing image failed to complete the evaluation, and other image examinations need to be added.

2. BI-RADS 1: normal, no abnormality was found in mammography. The possibility of malignancy is 0%.

3. BI-RADS 2: Benign findings, with definite benign changes and no malignant signs. The possibility of malignancy is 0%.

4. BI-RADS 3: Benign lesions that may be large. 0% < malignant possibility ≤2%.

5. BI-RADS 4: Suspected malignant lesions, but without typical malignant signs. 2% < malignant possibility < 95%.

6. BI-RADS 4A: low-grade suspected malignancy. 2% < malignant possibility ≤10%.

7. BI-RADS 4B: moderately suspected malignant. 10% < malignant possibility ≤50%.

8. BI-RADS 4C: highly suspected malignant. 50% < malignant possibility < 95%.

9. BI-RADS 5: Highly suggestive of malignant lesions with typical imaging features of breast cancer. Malignant possibility ≥95%.

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Classification of ultrasonic diagnosis results of breast

The classification of ultrasound evaluation refers to the screening of National Comprehensive Cancer Network (NCCN) and the BI-RADS classification standard proposed by American Radiological Society.

1. BI-RADS 0: The diagnostic information obtained by ultrasound is incomplete and cannot be evaluated, and it needs to be evaluated after other imaging examinations.

2. BI-RADS 1: negative, no abnormality was found by ultrasound. The possibility of malignancy is 0%.

3. BI-RADS 2: Benign lesions, with definite benign changes and no malignant signs. The possibility of malignancy is 0%.

4. BI-RADS 3: Benign lesions that may be large. 0% < malignant possibility ≤2%.

5. BI-RADS 4: Suspected malignant lesions, but without typical malignant signs. 2% < malignant possibility < 95%.

6. BI-RADS 4A: low-grade suspected malignancy. 2% < malignant possibility ≤10%.

7. BI-RADS 4B: moderately suspected malignant. 10% < malignant possibility ≤50%.

8. BI-RADS 4C: highly suspected malignant. 50% < malignant possibility < 95%.

9. BI-RADS 5: Highly suggestive of malignant lesions with typical imaging features of breast cancer. Malignant possibility ≥95%.

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Screening result management

1. BI-RADS 1 and BI-RADS 2 need no special treatment.

2.　BI-RADS 3：

The evaluation of mammography is BI-RADS 3, so it is advisable to reexamine the breast on the lesion side at the next 6 months, and reexamine the breast on both sides at the 12th and 24th months.

If the lesion remains stable, it can continue to be reexamined, and if it has not changed for 2-3 years, it can be reduced to BI-RADS 2. If the lesion disappears or shrinks during the reexamination, it can be directly evaluated as BI-RADS 2 or BI-RADS 1. Biopsy should be considered if suspicious findings are found in the lesions during the reexamination.

The breast ultrasound evaluation is BI-RADS 3, so it is advisable to have breast ultrasound reexamination in 3-6 months, and it can be reduced to BI-RADS 2 if there is no change after 2 years of follow-up.

3. BI-RADS 4A: Further imaging examination and biopsy are needed.

4. BI-RADS 4B: Further imaging examination is needed, and biopsy is appropriate.

5. BI-RADS 4C and BI-RADS 5: Biopsy should be performed.

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According to the standard, the breast physiological characteristics and breast cancer epidemic characteristics of women in China are quite different from those in western countries, so we can’t copy foreign experience. Establishing breast cancer screening standards suitable for women in China will play an important role in improving the scientificity, feasibility and practicability of breast cancer screening and reducing the incidence and mortality of breast cancer.

reference data

[1] He Jie, et al.,(2021). China female breast cancer screening standard (T/CPMA 014-2020). chinese journal of cancer prevention and treatment, DOI: 10.16073/J.CNKI.CJCPT.2021.01.02.

[2] Latest global cancer data: Cancer burden rises to 19.3 million new cases and 10.0 million cancer deaths in 2020. Retrieved Nov 16 ,2020, from https://www.iarc.fr/fr/news-events/latest-global-cancer-data-cancer-burden-rises-to-19-3-million-new-cases-and-10-0-million-cancer-deaths-in-2020/

Note: The purpose of this article is to introduce the progress of medical health research, not to recommend treatment schemes. For guidance on treatment plan, please go to a regular hospital.